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PharusDx, a CK Life Sciences and CK Hutchison investee, is developing a test that would provide fast, accurate diagnosis of not one but multiple types of cancer – all from a single blood sample. And it is using AI to do it.  

HUTCHMED’s global Phase III registration trial of its colorectal cancer-fighting drug, fruquintinib, aims to gain the regulatory approvals needed to bring it to cancer patients around the world. A 14-country study is the next step in bringing new options to doctors and new hope to families struggling with cancer.  

Patient access to novel treatments just got easier in parts of China. HUTCHMED’s surufatinib (SULANDA® in China) has been approved in the Macau Special Administrative Region. This drug has benefited over 12,000 patients with neuroendocrine tumours in China.

HUTCHMED’s first in-licensed product tazemetostat (TAZVERIK®) has been approved for use in Hainan Boao Lecheng International Medical Tourism Pilot Zone under the Clinically Urgently Needed Imported Drugs scheme. TAZVERIK® is a first-in-class EZH2 inhibitor that has been approved by the US Food and Drug Administration (FDA) for the treatment of certain patients with follicular lymphoma and advanced epithelioid sarcoma, a type of blood cancer and soft-tissue cancer, respectively.  

GAMECO, operating out of Guangzhou Baiyun International Airport since 1989, has signed two major agreements with the world-leading aircraft manufacturer, Boeing. A five-year contract will see them cooperate on the first integrated materials management partnership in Mainland China. Boeing will provide demand planning, on-site personnel and logistics services to support GAMECO’s operations to optimise materials purchase and inventory costs.

The other agreement will see the firms work together to expand their cooperation to convert passenger aircraft to freighters to match growing demand for cargo capacity, with B737-800 Boeing Converted Freighters (BCFs) and B767-300 BCFs being adapted. In fact, GAMECO just celebrated re-delivery of the first Boeing B767-300 BCF in Mainland China last month. Boeing forecasts demand for over 1,720 freighter conversions in the next 20 years.  

Authorities in the Macau Special Administrative Region have approved the commercialisation of ELUNATE® (fruquintinib). ELUNATE® gained its first approval in Mainland China by the National Medical Products Administration (“NMPA”) in September 2018 for the treatment of metastatic colorectal cancer. It is estimated that more than 40,000 patients have benefited from this novel treatment since its launch. It is the first homegrown innovative oncology drug to be marketed in Macau based on NMPA approval.

A new wave of HUTCHMED innovation is also on the way. In January 2022, sovleplenib was granted Breakthrough Therapy Designation by the NMPA. The designation allows accelerated development of new drugs that treat life-threatening diseases or serious conditions which lack effective treatment options. Sovleplenib has demonstrated encouraging results in patients with immune thrombocytopenia (“ITP”), an autoimmune bleeding disorder that can often have a significant, multifaceted impact on patients’ health and quality of life. It is now being studied in a China Phase III trial on ITP, along with additional studies on lymphoma ongoing in China, the US and Europe.  

China’s National Reimbursement Drug List aims to make life-saving drugs accessible to citizens in Mainland China and has expanded the number of HUTCHMED medicines on the list. The latest to be included is SULANDA® (surufatinib), following its approval for the treatment of advanced pancreatic neuroendocrine tumours. This latest update of the list also renewed ELUNATE® (fruquintinib), first included in 2020, for the treatment of metastatic colorectal cancer.  

Guangzhou Aircraft Maintenance Engineering Company (GAMECO) opened a new aircraft maintenance facility covering an area of over 98,000 square metres, with a roof big enough to accommodate six wide-body and five narrow-body aircraft under its capacious canopy. This increase in capacity will strengthen the Guangzhou airport economic zone as an important national centre for aircraft maintenance, helping China Southern Airlines’ fleet and supporting other customers in the region.  

HUTCHMED is now a constituent stock in the FTSE Russell’s Global Equity Index Series (GEIS), including FTSE All-World, FTSE Global All Cap, FTSE Global Total Cap and FTSE Global Mid Cap Indexes. The GEIS monitors more than 16,000 stocks in over 70 countries representing 98% of global market cap, making it a key indicator of global stock market direction.  

HUTCHMED is the new brand for the innovative biopharmaceutical business formerly known as Hutchison China MediTech. The company recently launched a successful listing on the Stock Exchange of Hong Kong (adding to its London AIM and Nasdaq presence), under the venerable stock code 13, which had been held by Hutchison Whampoa. It is now included in over 10 indexes including the Hang Seng Composite Index, the main board listing in Hong Kong, in addition to the Hang Seng Healthcare Index, and the Hang Seng Hong Kong-Listed Biotech Index. Mainland investors also have access to the stock through the Shanghai-Hong Kong Stock Connect and Shenzhen-Hong Kong Stock Connect programmes.  

Orpathys® (savolitinib, for lung cancer) and Sulanda® (surufatinib, for neuroendocrine tumours) have both been approved for use and then launched in Mainland China this year. Both drugs are unique, novel therapies created by HUTCHMED. Orpathys® is the only targeted medicine approved for these biomarker-selected patients in the Mainland. Sulanda®’s two recent approvals make it the first-ever drug launched to counter neuroendocrine tumours regardless of tumour origin, and approvals are also being sought in major jurisdictions such as the US and Europe.